We are working with the Centre for Fertility and Health (Norwegian Institute of Public Health), in a project called START; STudy of Assisted Reproductive Technology.
Here, we look at epigenetic and genetic differences between children conceived with assisted reproductive technology (ART) and normally conceived children to investigate possible short and long term effects, using a combination of data from registers, cohorts and biological samples.
Although most children born through ART are healthy, ART has been associated with increased risk of congenital malformations, infant morbidity and mortality. One proposed mechanism for the effects of ART procedures are epigenetic modifications of the DNA.
Increasing our knowledge concerning short and long term effects of ART is important, as the technology is increasingly used both in Norway and worldwide.